Identification and Biological Activities of the Phenolic Compounds in Eisenia arborea - American Journal of Plant Sciences

AJPS > Vol.12 No.2, February 2021

American Journal of Plant Sciences

Volume 12, Issue 2 (February 2021)

ISSN Print: 2158-2742 ISSN Online: 2158-2750

Google-based Impact Factor: 1.20 Citations h5-index & Ranking

Identification and Biological Activities of the Phenolic Compounds in Eisenia arborea ()

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Download as PDF (Size: 442KB) PP. 259-265

DOI: 10.4236/ajps.2021.122015 345 Downloads 864 Views Citations

Author(s)

Hyeon Cheol Shin¹, Ignacio Beamonte Wayas², Byoung Wook Choi³, Bong Ho Lee^3*

Affiliation(s)

¹CEWIT Center for Systems Biology, The State University of New York, 119 Songdo Moonhwaro, Yeonsu-gu, Incheon, Korea.
²Baja Kelp Talasoterapia, Ensenada, Mexico.
³Department of Chemical and Biological Engineering, Hanbat National University, 125 Dongseodaero, Yuseong-gu, Daejeon, Korea.

ABSTRACT

Four polyphenols were isolated and purified from a brown alga Eisenia arborea. These phlorotannin compounds showed strong radical scavenging and some enzyme inhibitory activities. All of the compounds showed strong antioxidative, acetylcholinesterase and butyrylcholinesterase inhibitory, and tyrosinase inhbibitory activities at 100 μg/mL. Dieckol and PFF inhibited butyrylcholinesterase, a new target for the treatment of Alzheimer’s disease, very strongly even at 10 μg/mL, more strongly than AChE. These two compounds also effectively inhibited tyrosinase. These results support the potential of developing natural antioxidants and antidementia agents from the brown alga.

KEYWORDS

Eisenia arborea, Phenolic Compounds, DPPH Radical Scavenger, Enzyme Inhibition, Isolation

Share and Cite:

Shin, H. , Wayas, I. , Choi, B. and Lee, B. (2021) Identification and Biological Activities of the Phenolic Compounds in Eisenia arborea. American Journal of Plant Sciences, 12, 259-265. doi: 10.4236/ajps.2021.122015.

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