Congenital Lipodystrophy: A Case Series Report from Cameroon - Open Journal of Pediatrics

OJPed > Vol.10 No.1, March 2020

Congenital Lipodystrophy: A Case Series Report from Cameroon ()

HTML XML

Download as PDF (Size: 247KB) PP. 231-235

DOI: 10.4236/ojped.2020.101023 461 Downloads 1,272 Views

Author(s)

Suzanne Sap Ngo Um^1,2*, Jocelyn Tony², Ritha Mbono³, Yannick Tekel², Isabelle Mekone^1,2, Mesmin Dehayem⁴, Koki Ndombo^1,2

Affiliation(s)

¹Department of Paediatrics, University of Yaounde I, Yaounde, Cameroon.
²Mother and Child Center of the Chantal Biya Foundation, Yaounde, Cameroon.
³University of Douala, Douala, Cameroon.
⁴Yaounde Central Hospital, Yaounde, Cameroon.

ABSTRACT

Congenital lipodystrophy is a group of rare syndrome characterized by the absence of subcutaneous tissue. Affecting less per million live birth, this condition associate metabolic disturbance including severe insulin resistance and progeroid appearance. Diagnosis may be fortuitous or related to complications as presented in the present case series. Lipodystrophy can be generalized or localized. Acquired lipodystrophy is associated with some drugs like antiretroviral. Thus, the condition is well described in African HIV patients but data on congenital forms from Sub Saharan Africa are sparse, justifying the present report. We present four cases, with peculiar appearance associated with increased blood triglycerides. Two on four of the patients presented diabetes mellitus. Genetic testing was not available, questioning the actual guidelines of diagnosis for our context.

KEYWORDS

Lipodystrophy, Diabetes, Children

Share and Cite:

Um, S. , Tony, J. , Mbono, R. , Tekel, Y. , Mekone, I. , Dehayem, M. and Ndombo, K. (2020) Congenital Lipodystrophy: A Case Series Report from Cameroon. Open Journal of Pediatrics, 10, 231-235. doi: 10.4236/ojped.2020.101023.

Journals Menu

Follow SCIRP

	+1 323-425-8868
	customer@scirp.org
	+86 18163351462(WhatsApp)
	1655362766

	Paper Publishing WeChat

Journals Menu

Home

About SCIRP

Service

Policies