Author(s)

F. L. F. Diakité^1*, P. Togo¹, A. K. Doumbia¹, F. Traoré¹, M. Traoré¹, K. Sacko¹, C. O. Coulibaly¹, N. L. Traoré¹, A. Touré¹, B. Maiga¹, L. N. Sidibé¹, D. Konaté¹, A. Diall¹, A. Dembélé¹, C. O. Coulibaly², C. B. Traoré³, B. Togo¹

¹Department of Pediatrics, CHU Gabriel Toure, Bamako, Mali.
²Department of Pediatric Surgery, CHU Gabriel Toure, Bamako, Mali.
³Department of Pathology Anatomy and Cytology, CHU Point G, Bamako, Mali.

The nephroblastoma is the third pediatric cancer in Mali, this study aimed to describe the prevalence and prognosis of nephroblastoma relapses. Methods: It was a descriptive retrospective study over a 10-year period from January 2005 to March 2015. We collected children aged 0 to 15 years followed for relapse of nephroblastoma in the pediatric oncology unit of university hospital center (UHC) Gabriel Toure. Results: The frequency of relapse of nephroblastoma was 7.4% (19 cases) whose mean age was 42 months with a sex ratio of 1.3. The relapse occurred before the end of the postoperative course in 16% of cases (3 patients). It was local recurrence in 52% of cases (10 patients), pulmonary 16% (3 patients), and hepatic 11% (2 patients). According to the SIOP classification, 47% of patients were diagnosed in stage III (9 patients) and 21% (4 patients) in stage IV. The tumor was high risk in 37%. Palliative chemotherapy was performed in 63% of the patients (12 patients) and the remaining seven were put on a high risk diet. The overall survival at 5 years was 21% or 4 patients. Conclusion: Our results showed all the difficulties in the management of nephroblastoma relapses in our context.

Nephroblastoma, Relapse, Mali

Diakité, F. , Togo, P. , Doumbia, A. , Traoré, F. , Traoré, M. , Sacko, K. , Coulibaly, C. , Traoré, N. , Touré, A. , Maiga, B. , Sidibé, L. , Konaté, D. , Diall, A. , Dembélé, A. , Coulibaly, C. , Traoré, C. and Togo, B. (2019) Prevalence and Prognosis of Relapse of Nephroblastoma at the Pediatric Oncology Unit of Bamako. Open Journal of Pediatrics, 9, 317-325. doi: 10.4236/ojped.2019.94031.