Isolation of Two Furanoditerpenes and Two Triterpenes from the Stem Bark of Dalbergia lanceolaria L.f. - Pharmacology & Pharmacy

PP > Vol.10 No.12, December 2019

Isolation of Two Furanoditerpenes and Two Triterpenes from the Stem Bark of Dalbergia lanceolaria L.f. ()

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DOI: 10.4236/pp.2019.1012043 604 Downloads 1,901 Views

Author(s)

Sharmin Sultana^1*, Fakir Shahidullah Tareq², Khondaker Miraz Rahman³, Choudhury Mahmood Hasan⁴

Affiliation(s)

¹Department of Pharmacy, University of Asia Pacific, Dhaka, Bangladesh.
²Department of Pharmacy, Manarat International University, Dhaka, Bangladesh.
³School of Cancer & Pharmaceutical Sciences, King’s College London, London, UK.
⁴Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka, Bangladesh.

ABSTRACT

Stem bark of Dalbergia lanceolaria was subjected to methanolic extraction and extensive phytochemical separation. The process yielded four known compounds namely Jateorin (1), Columbin (2), β-sitosterol (3), and Lupeol (4). The compounds were identified using nuclear magnetic resonance spectral data namely ¹H NMR, ¹³C NMR, ¹H-¹H COSY, HMBC, and DEPT-135 and verified by comparing the data with previous literature. All four compounds are being reported for the first time from the species D. lanceolaria. Furthermore, two furanoditerpenes namely Jateorin and Columbin are reported for the first time from the genus Dalbergia. This may lead to potential identification of a new chemotaxonomic marker for this genus.

KEYWORDS

Dalbergia lanceolaria, Fabaceae, Jateorin, Columbin, Furanoditerpene, ¹HNMR

Share and Cite:

Sultana, S. , Tareq, F. , Rahman, K. and Hasan, C. (2019) Isolation of Two Furanoditerpenes and Two Triterpenes from the Stem Bark of Dalbergia lanceolaria L.f.. Pharmacology & Pharmacy, 10, 519-527. doi: 10.4236/pp.2019.1012043.

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