Author(s)

Minqiang Liu¹, Mingfei Ma¹, Xinzhong Ning², Renliang He^1*

¹Department of Anesthesiology, The Third People’s Hospital of Shenzhen, Shenzhen, China.
²Department of Thoracic Surgery, The Third People’s Hospital of Shenzhen, Shenzhen, China.

Morphine is a potent opioid which is commonly used for relieving cancer pain with strong analgesic properties. Epithelioid hemangioendothelioma (EHE), a rare vascular tumor that can cause severe chronic pain, is usually diagnosed in a surgical biopsy. We describe ultrahigh doses of morphine used in a case of a 17-year-old male who suffered from severe chest pain with systemic multiple EHE. The total dosage of morphine was as high as 92,530 mg given within 164 days. However, we observed no indications that the patient was addicted.

Epithelioid Hemangioendothelioma, Morphine, Pain, Addiction

Liu, M. , Ma, M. , Ning, X. and He, R. (2019) Application of Ultrahigh Doses of Morphine in Systemic Multiple Epithelioid Hemangioendothelioma without Addiction: A Case Report. Case Reports in Clinical Medicine, 8, 285-294. doi: 10.4236/crcm.2019.811035.