Author(s)

Yawovi Mawufemo Tsevi^1*, Lidaw Deassoua Bawe², Komi Dzidzonu Nemi³, Akouda Patassi², Ihou Majesté Wateba²

¹Department of Nephrology and Hemodialysis, University Hospital Sylvanus Olympio of Lomé, University of Lome, Lome, Togo.
²Departement of Infectious and Tropical Diseases, University Hospital Sylvanus Olympio of Lomé, University of Lome, Lome, Togo.
³Department of Internal Medicine, University Hospital Sylvanus Olympio Lomé, University of Lome, Lome, Togo.

Introduction: Human Immunodeficiency (HIV) is a risk factor often associated with the occurrence of Acute Renal Failure (ARF). Objectives: To describe the profile of Acute Renal Failure (ARF) in HIV-infected patients and compare them to non-infected patients. Patients and Methods: It was a prospective study from January 2018 to February 2019 that took place in the nephrology, infectious diseases and internal medicine departments of the Sylvanus Olympio University Hospital Center in Lomé (Togo). Results: The prevalence of ARF in HIV-infected patients was 48.07%. HIV-infected patients had an average age of 46.9 ± 11.6 years (p = 0.36) compared to 44.0 ± 20.4 years for non-HIV infected patients. Female sex was predominant in the HIV-infected population with a sex ratio H/F of 0.6 (p < 0.0001) versus 2.9 for the non-infected. The reasons for admission were such as fever (28%), digestive disorders (56%) were more common in HIV-infected patients than non-infected patients (11.1%, 37%). Infected patients had more diarrhea than non-infected patients (24% versus 7.4%) with p = 0.01. They showed more signs of infections than uninfected patients (40% versus 18.5%) with P = 0.02. HIV infection was known before admission in 96% of cases. Patients whose HIV was known before admission had hypertension (16.7%), diabetes (12.5%) and CD4 count < 200 (/mm³) in 50% of cases. HIV infected patients had more anemia (52.0% versus 22.2%) with p = 0.002. Conclusion: No deaths were recorded in the HIV-infected group.

ARF, HIV, Togo

Tsevi, Y. , Bawe, L. , Nemi, K. , Patassi, A. and Wateba, I. (2019) Acute Renal Failure in Hospitals in Togo: Comparative Analysis of HIV Positive Patients and HIV Negative Patients. Open Journal of Nephrology, 9, 77-86. doi: 10.4236/ojneph.2019.93009.