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Four Cousins with Hypospadias, Is It Familial or Environmental? (Case Report)

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DOI: 10.4236/mps.2019.93008    152 Downloads   313 Views

ABSTRACT

Hypospadias is one of the most common birth defects. However, its etiology remains largely unknown. Genetic and also intrauterine environmental factors have a principal role in causing familial hypospadias. Hypospadias repair is done through several techniques, one of which is Snodgrass technique which has many advantages. The 4 cousins underwent repair with no complications during 6 months follow up period. Methods: Urethroplasty using Snodgrass hypospadias repair of 4 cousins with positive parental consanguinity and absent family history of hypospadias. Results: 4 cousins underwent Snodgrass (Tubularized incised plate urethroplasty) with no complications after 6 months follow up. Conclusion: Although there is high heritability of hypospadias that also aggregates within second- and third-degree relatives, environmental factors may play a principal role in causing familial hypospadias. Hypospadias repair has a long learning curve. The continuous auditing should be done to improve the results.

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Mohamed, M. , Senada, M. , Hassan, M. and Abdalazeem, Y. (2019) Four Cousins with Hypospadias, Is It Familial or Environmental? (Case Report). Modern Plastic Surgery, 9, 59-63. doi: 10.4236/mps.2019.93008.

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