Author(s)

Oscar R. Herrera^1,2*, Lisa A. Caviness¹, Richard A. Helms^1,2,3

¹Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center, Memphis, TN, USA.
²State of Tennessee Center for Pediatric Experimental Therapeutics, Memphis, TN, USA.
³Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA.

With the advent of new, particularly mixed-oil lipid emulsions approved by the United States Food & Drug Administration (FDA), clinicians have more options when choosing one as part of the parenteral nutrition support of patients. Lipid products long-standing availability in Europe and other parts of the world has certainly facilitated the process in the United States, where there was little evolution before 2014. These newer oil-based emulsions are finding their way to be used in pediatrics, as studies are being carried out that will result in pediatric labeling. Pediatric clinicians may find themselves wondering how these lipid emulsions are different from those that have come before; whether the same dosing or administration practices apply as with the traditional soybean-oil lipid emulsion, and if they can be used for other more emergent interventions. We present this review of the current lipid emulsions available in the U.S. market, highlighting the differences among them, as well as, providing some practical information for clinicians that can assist them in their day-to-day duties.

Lipid Emulsions, Fatty Acids, Parenteral Nutrition, Pediatrics

Herrera, O. , Caviness, L. and Helms, R. (2019) Emergence of New Injectable Lipid Emulsions in the USA: Guidance for Pediatric Clinicians. Food and Nutrition Sciences, 10, 823-833. doi: 10.4236/fns.2019.107060.