Author(s)

Juncheng Guo¹, Yijun Yang^1,2, Xiang Li³, Xiangling Jiang^2*, Min Guo², Zhuo Liu², Ping Huang², Jianhong Pan⁴

¹Xiangya School of Medical Affiliated Haikou Hospital, Central South University, Changsha, China.
²Department of Psychology, Hainan General Hospital, Haikou, China.
³The Third People’s Hospital of Hubei Province, Wuhan, China.
⁴Shanghai Jiao Tong University, Shanghai, China.

Posttraumatic stress disorder (PTSD) is to a persistently severe mental disorder which is caused by individual exposure to some unusual threatening or catastrophic stressful events. Its essential clinical manifestations refer to repeated playback of traumatic experience, durative avoidance of related clues, mental numbness or affection paralysis, and persistent increase of vigilance level. At present, the pathogenesis of PTSD has not been fully elucidated, and the clinical therapeutic effect has not been ideal. Generally, the classical animal model of PTSD is mouse; the domestic and international researches in the animal model of PTSD in recent years remain active, which are summarized as follows.

Post-Traumatic Stress Disorder, Animal Model, Review

Guo, J. , Yang, Y. , Li, X. , Jiang, X. , Guo, M. , Liu, Z. , Huang, P. and Pan, J. (2019) Research Progress on Post-Traumatic Stress Disorder and Its Animal Model. Journal of Behavioral and Brain Science, 9, 174-183. doi: 10.4236/jbbs.2019.94015.