Author(s)

Stéphane Méo Ikama^1*, Amorce Rolles Matingou¹, Jospin Makani¹, Norbert Lamini Nsounda², Solange Flore Mongo-Ngamami¹, Bertrand Fikhaem Ellenga-Mbolla¹, Louis Igor Ondze-Kafata¹, Thierry Raoul Gombet¹, Suzy Gisèle Kimbally-Kaky¹

¹Department of Cardiology, Brazzaville University Hospital Center, Brazzaville, Congo.
²Department of Rhumatolology, Brazzaville University Hospital Center, Brazzaville, Congo.

A longitudinal analytical and comparative study including outpatients was carried between June 1^st and December 31^st 2017. The objectives were to determine the hyperuricemia frequency during arterial hypertension, to identify associated factors, and to evaluate its impact on the blood pressure control. We have included, hypertensive patients having a minimum blood test including at least an uricemia. They were divided into two groups according to whether they have presented a hyperuricemia (HU) or a normouricemia (NU). Among these 202 patients included, 61 (30.2%) presented a hyperuricemia. The mean age in HU group was 54.6 ± 11.6 years vs 53.6 ± 11 years for NU group (p = 0.573). Following cardiovascular risk factors were more found in the HU group than NU group: overweight/obesity (68.8% vs 46.1%; p = 0.003), metabolic syndrome (42.6% vs 39%; p = 0.021). Diuretics were used in 72.1% of patients in HU group vs 47.5% in NU group (p = 0.002). Bitherapy was used in 56% of the patients of HU group vs 69% in the NU group (p = 0.295), and the quadritherapy in 8% and 1% of the patients respectively (p = 0.049). Blood pressure was not controlled in 68.8% of HU group vs 48.9% in the NU group (p = 0.014). In multivariate analysis after logistic regression, factors associated with hyperuricemia were: glucose intolerance or diabetes (p = 0.004; OR = 1.35) and uncontrolled blood pressure (p = 0.006; OR = 2.51). This preliminary study showed that hyperuricemia is commonly found in hypertensive patients and has negative impact on blood pressure control.

Hypertension, Hyperuricemia, Frequency, Blood Pressure Control, Congo

Ikama, S. , Matingou, A. , Makani, J. , Nsounda, N. , Mongo-Ngamami, S. , Ellenga-Mbolla, B. , Ondze-Kafata, L. , Gombet, T. and Kimbally-Kaky, S. (2019) Hyperuricemia and Associated Factors during Arterial Hypertension in Brazzaville (Congo). World Journal of Cardiovascular Diseases, 9, 236-244. doi: 10.4236/wjcd.2019.93021.