Author(s)

Ayse Z. Ozdemir¹, Bulent Ayas¹, Davut Guven¹, Abdulkadir Bakay², Pervin Karlı^3*

¹Ondokuz Mayis University IVF Center, Ondokuz Mayis University Hospital, Samsun, Turkey.
²Department of Obstetrics and Gynaecology, Ondokuz Mayis University Hospital, Samsun, Turkey.
³Amasya University, Department of Obstetrics and Gynecology, Amasya, Turkey.

Objective: This is a retrospective study to evaluate the effect of using the antioxidants containing coenzyme Q10 (CoQ10) and omega-3 in patients undergoing in vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI) for unexplained infertility. Materials Methods: A total of 299 patients undergoing IVF-ICSI for unexplained infertility at the IVF center of Ondokuz Mayis University were studied. The subject group consisted of 135 patients who used OMEPA Q10 (Co Q10 100 mg, omega-3 600 mg, eicosapentaenoic acid 300 mg, docosahexaenoic acid 230 mg) for two months before ovarian stimulation. A group of 164 patients who did not use the supplement were evaluated as the control group. Results: The pregnancy rate of patients using antioxidants was statistically higher than that of those who did not use the supplement (p < 0.05). The pregnancy rates of patients in the two groups were 32.9% and 49.6% respectively. The pregnancy rate of patients using antioxidants was statistically higher than that of those who did not use the supplement (p < 0.05) seemed not enough. Conclusion: We concluded that using antioxidants that contain Co Q10 and omega-3 in patients undergoing IVF-ICSI for unexplained infertility increased the clinical pregnancy rate. We recommend using antioxidants that contain Co Q10 and omega-3 in infertile patients.

CoQ10, Omega-3, Antioxidant, Unexplained Infertility, In Vitro Fertilization

Ozdemir, A. , Ayas, B. , Guven, D. , Bakay, A. and Karlı, P. (2019) Antioxidant Supplement Improves the Pregnancy Rate in Patients Undergoing in Vitro Fertilization for Unexplained Infertility. Open Journal of Obstetrics and Gynecology, 9, 1-9. doi: 10.4236/ojog.2019.91001.