Author(s)

Оlga А. Uspenskaya¹, Larisa N. Kazarina², Еlena А. Shevchenko³, Josef Herbert⁴

¹Department of Therapeutic Stomatology, Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia.
²Department of Propaedeutic Dentistry, Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia.
³Department of Pathological Physiology, Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical University» of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia.
⁴Dentist Running in Own Practice, Schönebeck, Germany.

This paper studied the dynamics of local immunity factors of the oral cavity in women with recurrent aphthous stomatitis against the background of urogenital infection. The research proves the maximum efficacy of hydroxyzine hydrochloride, aminodihydrophthalasindione sodium and Eplan used in multiple treatments of recurrent aphthous stomatitis in patients with urogenital infection as evidenced by a marked reduction in the coefficient of local immunity factors balance, which is observed as early as on day 7 of the therapy provided. Moreover, the findings show the growth of immunological parameters of oral fluid (lysozyme and SIgA), the normalization of the coefficient of local immunity factors balance in the treatment of recurrent aphthous stomatitis in women with urogenital infection, the improvement being observed 3 months after the treatment suggesting a favorable local immunity of the oral cavity.

Hydroxyzine Hydrochloride, Aminodihydrophthalasindione Sodium, Eplan, Chronic Recurrent Aphthous Stomatitis, Coefficient of Local Immunity Factors Balance, Secretory IgA, Lysozyme, Immunoglobulin A, G

Uspenskaya, О. , Kazarina, L. , Shevchenko, Е. and Herbert, J. (2019) The Local Immunity of the Oral Cavity in Women with Recurrent Aphthous Stomatitis Associated with Urogenital Infection. Open Journal of Stomatology, 9, 1-8. doi: 10.4236/ojst.2019.91001.