Author(s)

Xue Fu^1,2, Bo Song^1,2, Xiaozhen Chen², An Wang^1*, Chun Wang^2*

¹College of Architecture and Environment, Sichuan University, Chengdu, China.
²Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.

A highly-controllable core-shell silica-MIPs absorbent by anchoring a MIPs layer to the surface of SiO₂ nanoparticles via a surface molecular imprinting process was prepared. The templates were covalently modified with functional monomers to form precursor EstSi. The latter together with coupling reagent KH-570, were grafted onto the surface of SiO₂ nanoparticles before polymerization, to ensure the quantity and quality of imprinted sites on the surface of the covalently attached matrix. The as-synthesized core-shell nanomaterials (SiO₂@MIP2) were then evaluated for selective adsorption of 17β-estradiol (E2) with Raman spectra as detection method. The results indicate that SiO₂@MIP2 can fast and selectively adsorb E2 from structural analogues, with detection limit of 0.01 μmol/l.

Surface-Imprinting, Core-Shell Nanoparticle, Selective Adsorption, 17β-Estradiol

Fu, X. , Song, B. , Chen, X. , Wang, A. and Wang, C. (2018) Highly-Controllable Imprinted Polymer Nanoshell on the Surface of Silica Nanoparticles for Selective Adsorption of 17β-Estradiol. Journal of Encapsulation and Adsorption Sciences, 8, 210-224. doi: 10.4236/jeas.2018.84011.