Author(s)

Khardiata Diallo Mbaye^1*, Ndèye Aissatou Lakhe¹, Khadime Sylla², Rahmatoulahi Ndiaye¹, Viviane Marie Pierre Cissé Diallo¹, Daye Ka¹, Aminata Massaly¹, Alassane Dièye¹, Louise Fortes Déguénonvo¹, Cheikh Tacko Diop³, Cheikh Tidiane Ndour¹, Masserigne Soumaré¹, Moussa Seydi¹

¹Clinic of Infectious Diseases, Fann National University Hospital, Dakar, Senegal.
²Laboratory of Parasitology-Mycology, Faculty of Medicine, Cheikh Anta Diop University, Dakar, Senegal.
³CommunityHealthDepartment, Health and SustainableDevelopment Training Unit and Research, Alioune Diop University, Bambey, Senegal.

Introduction: Entero bacteria are mainly found in the gut of man and animals. The frequent acquisition of antibiotic resistance mechanisms explains why they are the bacteria most often implicated in human infectious pathology. It is estimated to be involved in 50% of sepsis, 60% of enteritis, 70% of urinary tract infection case. Objective: To determine the prevalence of enterobacterial infections diagnosed at Fann Infectious Diseases Clinic, and describe their epidemiological, clinical, therapeutic and evolutionary aspects. Patients and Methods: This is a retrospective and descriptive study, on patients hospitalized from January 2013 to December 2014, at Fann Infectious Diseases Clinic, with bacteriological confirmation of an enterobacteria infection. Results: A total of 129 cases were collected during the study period. The average age was 41 years, and female were predominant (60%) with a sex ratio of 0.67. Comorbidity was found in 88.4% of the cases, most of which were HIV infection. The most common clinical signs were infectious syndrome (53.49%) and general impairment (40.31%). The main gateway was urinary (55.8%). Samples were monomicrobial in 76.7% of cases. Klebsiella and Escherichia were the most common and 68.7% of the subjects had probabilistic treatment. Most enterobacterial strains were resistant to third generation cephalosporins (C3G), aminoglycosides to ciprofloxacin and cotrimoxazole. Aside from 4% of them, all were sensitive to imipenem. Conclusion: The advent of antibiotics has brought hope in the treatment of enterobacterial infections. However, an increase in their resistance to the usual antibiotics has been noted in recent years. As a result, the fight against antibiotic resistance must be a priority.

Dakar, Enterobacteria, Infections, Senegal

Mbaye, K. , Lakhe, N. , Sylla, K. , Ndiaye, R. , Diallo, V. , Ka, D. , Massaly, A. , Dièye, A. , Déguénonvo, L. , Diop, C. , Ndour, C. , Soumaré, M. and Seydi, M. (2018) Enterobacterial Infections Diagnosed at the Clinic of Infectious Diseases of Fann Hospital (2013-2014) Dakar, Senegal. Advances in Infectious Diseases, 8, 217-228. doi: 10.4236/aid.2018.84018.