Author(s)

Golder N. Wilson^*, Vijay S. Tonk

Department of Pediatrics, Texas Tech University Health Science Centers, Lubbock, USA.

Genomic analysis has emphasized the enormous genetic contribution to autism spectrum disorders, with over 80% of patients having changes demonstrable by high resolution chromosome (microarray) analysis or whole exome sequencing. An overview of these genetic changes demonstrates the expected role of synaptic transmission in autism and, together with clinical observations, emphasizes the importance of visual input on developing sensory systems and social responses. Neonatal recognition of autism predisposition through genetic analysis could allow sensory stimulation therapies during periods of neuroplasticity, an approach analogous to strabismus correction before the cortical dissociation of the deviant eye.

Autism, Autism Spectrum Disorders, Genomics, Array-Comparative Genomic Hybridization, Microarray Analysis, Whole Exome Sequencing, Synaptic Transmission

Wilson, G. and Tonk, V. (2018) Autism: A Different Vision. Open Journal of Psychiatry, 8, 263-296. doi: 10.4236/ojpsych.2018.83023.