Author(s)

V. Esther Rani^*, P. Raveendra Reddy

Department of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India.

The most important nitrogen containing heterocycles of pyridine containing substituted phenyl azetidine-2-ones have found pharmacological application such as antibiotics and these compounds also have practical importance. The structure of the new derivatives was confirmed by the spectral data and elemental analyses. Out of five new derivatives, three were revealed mild to moderate activity compared with Streptomycin & Fluconazole as a reference standard. Among this new series, 3-chloro-1-(4-fluoro phenyl)/(4-chloro phe-nyl)-4-(pyridine-3-yl) azetidine-2-one (4a & b) were found most activity.

Antibacterial, Antifungal, Azetidin-2-One, Pyridine

Rani, V. and Reddy, P. (2018) Synthesis and Antimicrobial Activity of New Pyridine Containing Substituted Phenyl Azetidine-2-One Derivatives. Open Journal of Medicinal Chemistry, 8, 22-29. doi: 10.4236/ojmc.2018.82003.