Author(s)

Todor Deligeorgiev, Stefka Kaloyanova, Nedyalko Lesev, Ramón Alajarín, Juan J. Vaquero, Julio Álvarez-Builla

.

An improved environmentally benign procedure for synthesis of substituted 2-cyanomethyl-4-phenylthia- zoles under focused microwave irradiation using glycerol as solvent has been carried out. The method allows the synthesis of products in excellent yields with short reaction times and the work-up is easy. This approach can be applied to the preparation of a variety of derivatives.

2-Cyanomethyl-4-Phenylthiazoles, Microwave Synthesis, Glycerol, Green Chemistry

T. Deligeorgiev, S. Kaloyanova, N. Lesev, R. Alajarín, J. Vaquero and J. Álvarez-Builla, "An environmentally Benign Synthesis of 2-Cyanomethyl-4-Phenylthiazoles under FocusedMicrowave Irradiation," Green and Sustainable Chemistry, Vol. 1 No. 4, 2011, pp. 170-175. doi: 10.4236/gsc.2011.14026.