Landslide is one of the most harmful geological disasters for long-distance oil and gas pipelines, and evaluating pipeline vulnerability in case of landslide consequently plays an important role in improving the landslide risk assessment level. To ensure creditability, applicability and operability of pipeline vulnerability evaluation results, a physical simulation test based on the similarity principle was carried out between landslide and pipeline to verify the deformation behavior, stress and strain distribution status of pipeline in case of landslide and to acquire the empirical formula of pipeline vulnerability and distribution of thrust applied on the pipeline by landslide.