Author(s)

Bertrand Fikahem Ellenga Mbolla^1*, Paul Macaire Ossou Nguiet¹, Richard Loumingou¹, Meo Stéphane Ikama¹, Narcisse Ngangoue², Thierry Raoul Gombet¹, Henri Germain Monabeka¹, Benjamn Longo Mbenza³, Gisèle Kimbally Kaky¹

¹Department of Doctoral Studies, Faculty of Health Sciences, Marien Ngouabi University of Brazzaville, Brazzaville, Congo.
²Laboratoire de biochimie CHU de Brazzaville, Brazzaville, Congo.
³Faculty of Health Sciences, Walter Sisulu University, Queenstown, Eastern Cape, South Africa.

The authors conducted a retrospective study over a period of 6 months in a hypertensive population in order to determine the correlation between serum uric acid on glomerular filtration rate (GFR) and estimated serum potassium with left ventricular hypertrophy (LVH) and obesity. This study enrolled 122 patients including 63 women (51.6%). The mean age was 55.9 ± 10.6 years (range 30 to 74 years). Obesity weight was found in 38 cases (31.1%) of which 20 were men (33.9%) and 18 women (28.6%). Abdominal obesity was found in 104 cases (85.2%). The average serum uric acid in patients with obesity weight was 63.3 ± 18.9 mg/L vs 62.4 ± 14.2 mg/L for no-obese patients (p = 0.63). The average serum potassium in obese patients was 4.06 ± 0.42 mEq/L vs 4.02 ± 0.46 mEq/L for no-obese (p = 0.65). The average GFR was 73.4 ± 21.4 ml/L in obese patients vs 66.6 ± 22.6 ml/min in no-obese (p = 0.03). The LVH was found in 81 cases (66.4%). The LVH was found in 65 (62.5%) obese patients vs 16 (88%) non-obese patients (OR = 4.8, 95% 1.04 - 22 p = 0.02). Only abdominal obesity has been correlated with left ventricular hypertrophy after multivariate analysis. Emphasis must be focused on public health actions for effective and appropriate measures against obesity and hypertension, whose prevalence is increasing in our region.

Obesity, High Blood Pressure, Glomerular Filtration Rate, Uric Acid, Serum Potassium, Black African

Ellenga Mbolla, B. , Ossou Nguiet, P. , Loumingou, R. , Ikama, M. , Ngangoue, N. , Gombet, T. , Monabeka, H. , Mbenza, B. and Kaky, G. (2018) Relationship between Obesity, Serum Uric Acid, Serum Potassium and Glomerular Filtration Rate with Electric Left Ventricular Hypertrophy in Blacks Central Africans with High Blood Pressure. World Journal of Cardiovascular Diseases, 8, 248-255. doi: 10.4236/wjcd.2018.84024.