Based on the questionnaire of 207 enterprise employees in South China, this paper uses the method such as hierarchical regression analysis, to explore the relationship between career growth and work engagement, the intermediary role of organizational identification and the moderating effect of person- organization value fit. The study shows that: 1) Employee career growth has a significant positive impact on organizational identification and work engagement; 2) Organizational identification plays a partial mediating role between career growth and work engagement; 3) Person-organization value fit positively regulates the relationship between career growth and organizational identification. That is to say, the higher the person-organization value fit, the more obvious the influence of career growth on organizational identification. Finally, based on the results, the paper discusses the significance of this research in theory and practice.