Ionic Liquid Based Ultrasonic-Assisted Extraction of Oleanolic Acid from Grape Seeds - Open Access Library Journal

OALibJ > Vol.4 No.12, December 2017

Ionic Liquid Based Ultrasonic-Assisted Extraction of Oleanolic Acid from Grape Seeds ()

HTML XML

Download as PDF (Size: 5925KB) PP. 1-16

DOI: 10.4236/oalib.1104148 522 Downloads 1,496 Views Citations

Author(s)

Xifeng Zhang^1,2, Xue Li¹, Qian He¹, Bin Zhang¹, Xue Zheng^1,2

Affiliation(s)

¹The College of Agriculture and Biotechnology (CAB), Hexi University, Zhangye, China.
²Key Laboratory of Hexi Corridor Resources Utilization of Gansu, Zhangye, China.

ABSTRACT

Ionic liquid based ultrasonic-assisted extraction (ILUAE) was successfully applied to extract Oleanolic acid (OA) from grape seeds. Different kinds of 1-alkyl-3-methylimidazolium ionic liquids with different kinds of cations and anions were studied and 1-butyl-3-methylimidazolium chloride ([C₄mim]Cl) solution was selected as extractants. The optimal conditions of ILUAE were determined by single factor experiments and Box-Behnken design as follows: [C₄mim]Cl concentration of 0.7 mol/L, extraction time of 4 h, liquid-solid ratio of 15:1 mL/g, ultrasonic power of 195 W, the ultrasonication time of 13 min, and extraction temperature of 48℃·min. The extraction yield of OA was 13.4 mg/g, which is well in close agreement with the value predicted by the model. Compared with the regular ultrasonic-assisted extraction (UAE), the proposed approach exhibited 1.64 times higher efficiency, which indicated that ILUAE has a broad prospect for sample preparation of the bioactive compounds.

KEYWORDS

Ionic-Liquid Based Ultrasound-Assisted (ILUAE), Oleanolic Acid, Grape Seeds

Share and Cite:

Zhang, X. , Li, X. , He, Q. , Zhang, B. and Zheng, X. (2017) Ionic Liquid Based Ultrasonic-Assisted Extraction of Oleanolic Acid from Grape Seeds. Open Access Library Journal, 4, 1-16. doi: 10.4236/oalib.1104148.

Journals Menu

Follow SCIRP

	+1 323-425-8868
	customer@scirp.org
	+86 18163351462(WhatsApp)
	1655362766

	Paper Publishing WeChat

Journals Menu

Home

About SCIRP

Service

Policies