Author(s)

Kuo-Chen Chou, Wei-Zhong Lin, Xuan Xiao

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The wenxiang diagram was proposed to represent α-helices in a 2D (two dimensional) space (Chou, K.C., Zhang, C.T., Maggiora, G.M. Proteins: Struct., Funct., Genet., 1997, 28, 99-108). It has the capacity to provide more information in a 2D plane about each of the constituent amino acid residues in an α-helix, and is particularly useful for studying and analyzing amphiphilic helices. To meet the increasing requests for getting the program of generating wenxiang diagrams, a user-friendly web-server called “Wenxiang” has been established. It is accessible to the public at the web-site http://www.jci-bioinfo.cn/wenxiang2 or http://icpr.jci.edu.cn/bioinfo/wenxiang2. Further- more, for the convenience of users, here we provide a step-to-step guide for how to use the Wenxiang web-server to generate the desired wenxiang diagrams.

Amphiphilic Helix; Helix-Helix Interaction; Hydrophobic; Hydrophilic; 2D Diagram; Wenxiang Diagram; Helical Wheel Diagram

Chou, K. , Lin, W. and Xiao, X. (2011) Wenxiang: a web-server for drawing wenxiang diagrams. Natural Science, 3, 862-865. doi: 10.4236/ns.2011.310111.