A Deterministic Mathematical Model for Direct and Indirect Transmission Dynamics of Typhoid Fever - Open Access Library Journal

OALibJ > Vol.4 No.5, May 2017

A Deterministic Mathematical Model for Direct and Indirect Transmission Dynamics of Typhoid Fever ()

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DOI: 10.4236/oalib.1103493 1,898 Downloads 5,093 Views Citations

Author(s)

Stephen Edward

Affiliation(s)

Department of Mathematics, University of Dodoma, Dodoma, Tanzania.

ABSTRACT

Improvements in sanitation and the provision of clean drinking water led to the elimination of typhoid fever from developed countries in the beginning of the 20th century. However, Salmonella typhi and paratyphi remain a major source of morbidity and mortality in many developing countries today. The dynamics of typhoid transmission are poorly understood. In this study, we develop a novel mathematical model that captures the role of both human to human interaction and human to environment interaction in the transmission dynamics of typhoid fever. Our results have shown the feasible impact of different methods of typhoid control, including vaccination, improved treatment strategies, and investment in clean water and sanitation.

KEYWORDS

Modeling, Sanitation, Treatment, Vaccination, Epidemiology, Typhoid

Share and Cite:

Edward, S. (2017) A Deterministic Mathematical Model for Direct and Indirect Transmission Dynamics of Typhoid Fever. Open Access Library Journal, 4, 1-16. doi: 10.4236/oalib.1103493.

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