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Esophageal Cancer in Sudan: Demographic and Histopathlogical Variations

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DOI: 10.4236/ojgas.2017.73014    999 Downloads   1,729 Views Citations

ABSTRACT

Background: Sudan is experiencing a growing cancer problem. Esophageal cancer (EC) is a devastating disease with high mortality. Our objective was to study the demographic factors and histopathological pattern of EC cancer in Khartoum, Sudan. Methods: In a retrospective cross-sectional study, the records and histopathology reports of all patients diagnosed endoscopically as EC and who were referred to Zain center, a reference histopathology center in Khartoum Sudan, were studied over a 6-month period. Descriptive and simple statistics were used for analysis. Results: Out of 74 histopathologically studied patients, 66 (89.2%) had squamous cell (SCC) cancer (average age 59 y, mainly females) and 8 (10.8%) had adenocarcinoma (AC-average age 69 y). The female to male ratio is 1.5:1. In females with SCC, the tumors mainly located in the upper and middle thirds of the oesophagus. On the other hand, 6 out of the 8 patients with AC were men, with the tumors located mainly in the lower third. Conclusions: In Khartoum, Sudan, esophageal cancer affects females (predominantlySCC) more than males (predominantly AC). It occurs at a relatively young age, and is predominantly squamous cell in type. No specific risk factors were identified and this needs further studies.

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Hamad, A. , Ahmed, M. , Abdelgadir, A. and Suliman, I. (2017) Esophageal Cancer in Sudan: Demographic and Histopathlogical Variations. Open Journal of Gastroenterology, 7, 124-129. doi: 10.4236/ojgas.2017.73014.

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