Author(s)

Kenichi Itao^1,2, Makoto Komazawa¹, Zhiwei Luo³, Hiroyuki Kobayashi²

¹WINFrontier Co. Ltd., Tokyo, Japan.
²Juntendo University, Tokyo, Japan.
³Organization of Advanced Science and Technology, Kobe University, Kobe, Japan.

This study used a small wearable heart rate sensor to monitor the daily autonomic function of 600 subjects from across all age groups over a prolonged period of time. The results indicated that the LF/HF ratio (Heart Rate Variability, LF: frequencies between 0.04 Hz - 0.15 Hz, HF: frequencies between 0.15 Hz - 0.4 Hz) an indicator of balance in the autonomic nervous system, tended to peak for subjects in their 40’s and decline thereafter. This conceivably may be partially due to the causes for concern and stress changing and/or declining for the group aged 50-plus. A decline in diurnal variation of autonomic nervous activity was also exhibited in subjects aged 50 and up, showing a tendency for decline in the function of rising sympathetic nerve activity particularly in the morning. It is conceivable that this stems from a decline in the responsiveness of the autonomic nervous system. Subjects in the 50-plus group furthermore exhibited a tendency for declining variation in autonomic nervous activity between sleeping and waking hours. This phenomenon was consistent with the tendency for there to be a rise in wake after sleep onset coupled with a decline in slow-wave sleep in middle- to old-age.

Heart Rate Variability, Autonomic Nervous System, Stress, Age, Circadian Rhythm, Sleep

Itao, K. , Komazawa, M. , Luo, Z. and Kobayashi, H. (2017) Long-Term Monitoring and Analysis of Age-Related Changes on Autonomic Nervous Function. Health, 9, 323-344. doi: 10.4236/health.2017.92023.