Author(s)

Hirohito Sugawara^1*, Hideki Takizawa¹, Norihito Moniwa¹, Naoki Takamatsu², Yusuke Ohashi², Yayoi Ogawa³

¹Department of Nephrology, Teine-Keijinkai Hospital, Sapporo, Japan.
²Department of General Internal Medicine, Teine-Keijinkai Hospital, Sapporo, Japan.
³Hokkaido Renal Pathology Center, Sapporo, Japan.

We report a case of IgG4-related disease presenting both tubulointerstitial nephritis and retroperitoneal fibrosis causing acute renal failure in a 63-year-old male. He was admitted to our hospital because of acute renal failure requiring emergent hemodialysis. Computed tomography showed a soft-tissue density mass with an irregular border in the retroperitoneum. The mass involved bilateral ureters and had caused acute renal failure by bilateral hydronephrosis. Because of a history of uveitis and high IgG4 levels, we considered a diagnosis of retroperitoneal fibrosis, IgG4-related disease. Kidney biopsy revealed IgG4-related kidney disease with interstitial nephritis. After relief of urinary obstruction by inserting ureteral catheters into the bilateral ureters, renal function recovered.

IgG4 Related Disease, IgG4 Related Tubulointerstitial Nephritis, Retroperitoneal Fibrosis, Acute Renal Failure

Sugawara, H. , Takizawa, H. , Moniwa, N. , Takamatsu, N. , Ohashi, Y. and Ogawa, Y. (2016) A Case of Acute Renal Failure Associated with IgG4-Related Disease Presenting Both Tubulointerstitial Nephritis and Retroperitoneal Fibrosis. Open Journal of Nephrology, 6, 86-92. doi: 10.4236/ojneph.2016.63011.