Author(s)

Maduike C. O. Ezeibe¹, Dahiru Aleeyu², Nnaemeka K. Aneke³, Thompson N. Obarezi³, Ijeoma J. Ogbonna¹, Ekenma Kalu¹

¹College of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike, Nigeria.
²Basic Health Clinic, Abuja, Nigeria.
³Medical Centre, Michael Okpara University of Agriculture, Umudike, Nigeria.

HIV/AIDS patients were treated, daily, with MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra-protectionM^? (1 tablet), for one month and then, with only MSAMS and the immune stimulants. They were tested, monthly, for viral loads and CD4- lymphocytes counts. Those whose viral loads became undetectable were tested for HIV confirmation (antigens/antibody). Their mean-viral load increased (P = 0.020) from 1820.30 ± 868.75 to 2855.90 ± 960.98 after first month, before reducing (P = 0.0.030) to: 1565.20 ± 743.17; 759.20 ± 473.65; 345.50 ± 115.01; 192.80 ± 97.40; 95.00 ± 55.80; 37.40 ± 26.46; 17.50 ± 16.88 (undetectable). Their mean-CD4 count was 496.80 ± 194.39 (lymphopenia). It reduced (P = 0.008) to 263.90 ± 149.26 after first month, before increasing (P = 0.001) to: 507.90 ± 133.19; 692.70 ± 113.34; 840.20 ± 139.41; 1007.30 ± 163.50; 1537.10 ± 302.10; 1924.60 ± 247.45; 2707.00 ± 837.87 (lymphocytosis). Patients whose viral loads became undetectable tested HIV-negative, one month after. CD4-lymphocytes count, approximating to zero-viral load, calculated from equation (Y = 2297.80 － 1.4731X) of line of best fit of graph of their viral loads onCD4-lymphocytes counts, was 1559.84/ml.

HIV, MSAMS-Nanoparticles, Opposite Electrical Charges, HIV-Positive, Lymphopenia, HIV-Antigens/Antibody Negative, Lymphocytosis

Ezeibe, M. , Aleeyu, D. , Aneke, N. , Obarezi, T. , Ogbonna, I. and Kalu, E. (2016) Assessment of Antiretroviral Efficacy of the Medicinal Synthetic Aluminum-Magnesium Silicate {Al₄(SiO₄)₃ + 3Mg₂SiO₄ → 2Al₂Mg₃(SiO₄)₃}. World Journal of AIDS, 6, 74-80. doi: 10.4236/wja.2016.62011.