Author(s)

Tingting Cui^1*, Chao Wang², Changsong Shan¹, Peng Wu^1*

¹College of Food Science and Technology, Shandong Agriculture University, Taian, China.
²College of Horticulture Science and Engineering, Shandong Agricultural University, Taian, China.

The ultrasound-assisted extraction of chlorogenic acid from honeysuckle was modeled using response surface methodology. A three-level-three-factor Box–Behnken design was employed to optimize three extraction variables, including extraction temperature (X₁), ethanol concentration (X₂), and soak time (X₃), for the achievement of high extraction yield of the chlorogenic acid. The optimized conditions are extract temperature of 80℃, ethanol concentration of 70.37%, soak time of 9.35 h. Under this optimized conditions, the experimental yield of chlorogenic acid is 1.918%, which is well matched with the predicted yield of 1.929%.

Design-Expert Software, Lonicera Japonica, Chlorogenic Acid, Extraction Technology Optimization

Cui, T. , Wang, C. , Shan, C. and Wu, P. (2014) Optimization of the Extraction Technology of Chlorogenic Acid in Honeysuckle by Response Surface Method. Open Access Library Journal, 1, 1-9. doi: 10.4236/oalib.1100941.