Author(s)

Masaaki Minami^1*, Ryoko Sakakibara², Taichi Imura², Mika Watanabe², Hideo Morita², Naoto Kanemaki³, Michio Ohta⁴

¹Department of Bacteriology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
²Department of Clinical Investigation, Daido Hospital, Nagoya, Japan.
³Department of Gastroenterology, Daido Hospital, Nagoya, Japan.
⁴School of Nursing, Sugiyama Jyogakuen University, Nagoya, Japan.

Streptococcus pyogenesis most popularpathogen caused respiratory tract infection disease. This study was conducted to find out the recent clinical characteristics of Streptococcus pyogenes isolates from respiratory tract at Japanese hospital in 2014. Streptococcus pyogenes was identified by standard laboratory procedure. Antimicrobial susceptibility testing was performed by micro dilution assay according to CLSI recommendation. Respiratory tract isolates were defined as isolation from pharynx, nasal discharge, tonsillar, and sputum. Total one hundred sixty-one Streptococcus pyogenes were isolated among which 136 were from respiratory tract and 25 were from non- respiratory tract. Respiratory tract-associated Streptococcus pyogenes was isolated among which 102 were from male and 59 were from female. The age incidence among 0 - 1 years age group was 8, among 1 - 18 years age group, 131 (p < 0.01), among 19 - 64 years age group, 17 (p < 0.01), and in 65-years it was 5. Although we investigated the relationship between season and bacterial isolation, we did not find any significant differences between respiratory tract and no respiratory tract isolation. However, our study revealed that clarithromycin was less antimicrobial effective in respiratory tract disease than in no respiratory tract disease significantly (p < 0.01). Although several antibiotics such as penicillin are still effective against Streptococcus pyogenes, incidence of Streptococcus pyogenes infection is not decreasing worldwide. Our study suggests the need for continuous epidemiological surveillance of Streptococcus pyogenes.

 

Streptococcus pyogenes, Susceptibility, Antimicrobial Resistance, Epidemiology, Clarithromycin

Minami, M. , Sakakibara, R. , Imura, T. , Watanabe, M. , Morita, H. , Kanemaki, N. and Ohta, M. (2015) Clinical Characteristics of Respiratory Tract-Associated Streptococcus pyogenes at General Japanese Hospital in 2014. Journal of Biosciences and Medicines, 3, 26-31. doi: 10.4236/jbm.2015.312005.