Author(s)

William Kofie^1,2*, Stephen Caddick^2,3

¹Centre for Drug Design and Development, Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
²Centre for Biomolecular Design and Drug Development, The Chemistry Laboratory, CPES, University of Sussex, Brighton, UK.
³Department of Chemistry, University College London, London, UK.

The use of intramolecular reactions involving palladium/imidazolium salts to synthesize hetero-cyclic compounds is described. Reactivity of phenyl, ethyl and methyl substituents leading to isolation of various isomeric products is also illustrated. Rearrangement of phenyl intermediates to furnish benzoxazoles is also mentioned.

N-Heterocyclic Carbenes, Heterocyclic Systems, Imidazolium Salt, Intramolecular Cyclicsations, Phosphine Ligands

Kofie, W. and Caddick, S. (2015) Palladium/Imadazolium Salt Mediated Cyclisations for the Synthesis of Heterocyclic Compounds. International Journal of Organic Chemistry, 5, 223-231. doi: 10.4236/ijoc.2015.54022.