Effect of Carotid Artery Stenting and Extracranial-Intracranial By-Pass on Cognitive Function: Preliminary Results - International Journal of Clinical Medicine

IJCM > Vol.6 No.6, June 2015

Effect of Carotid Artery Stenting and Extracranial-Intracranial By-Pass on Cognitive Function: Preliminary Results ()

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DOI: 10.4236/ijcm.2015.66049 2,645 Downloads 3,363 Views Citations

Author(s)

Li Liu¹, Yuying Zhou^2*

Affiliation(s)

¹Department of Radiology, Tianjin Huan Hu Hospital, Tianjin, China.
²Department of Neurology, Tianjin Huan Hu Hospital, Tianjin, China.

ABSTRACT

Background: To compare the neuropsychological consequences after carotid artery stenting (CAS) and extracranial-intracranial by-pass (EC-IC by-pass). Methods: A total of 43 patients referred to CAS, 32 patients referred to EC-IC by-pass and 43 control subjects were enrolled in the study. Neuropsychologic testing was performed before and three months after procedure. A paired Student t test was used to compare neuropsychologic test scores at baseline and three months after procedure in each group. Cognitive changes in a three-month follow-up were not normally distributed and compared among/between groups with Kruskal-Wallis test. Results: Three months after the treatment both the CAS and EC-IC by-pass groups showed improved cognitive performance compared to baseline, whereas the same improvement wasn’t seen in the control group. The scores from Activities of Daily Living also improved in all three groups in a three-month follow-up, and EC-IC group presented a more distinct increase in daily life abilities comparing to the other two groups. Conclusions: CAS and EC-IC by-pass in patients with a carotid or intracranial stenosis may result in cognitive improvement three months after surgery.

KEYWORDS

Carotid Artery Stenting, Extracranial-Intracranial By-Pass, Cognition

Share and Cite:

Liu, L. and Zhou, Y. (2015) Effect of Carotid Artery Stenting and Extracranial-Intracranial By-Pass on Cognitive Function: Preliminary Results. International Journal of Clinical Medicine, 6, 377-383. doi: 10.4236/ijcm.2015.66049.

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