Author(s)

Belén Gastaca¹, Gastón Galletti¹, Hernán Rubén Sánchez², Reinaldo Pis Diez², María de las Mercedes Schiavoni¹, Jorge Javier Pedro Furlong^1*

¹Laboratorio de Estudio de Compuestos Orgánicos (LADECOR), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.
²CEQUINOR, Centro de Química Inorgánica (CONICET, UNLP), Facultad de Ciencias Exactas, UNLP, La Plata, Argentina.

The mass spectral fragmentation of thiosemicarbazones synthesized from acetophenones has been studied by CG/MS. These carbonyl compounds exhibit chromatographic peaks which are not observed in aliphatic analogues or those synthesized from aldehydes. The analysis of the corresponding spectra has allowed structural assignment to the dimerization of gas phase neutral fragments. Theoretical calculations (DFT level) also provide evidence to support the experimental observations.

Thiosemicarbazones, Mass Spectrometry Analyses, Dimerization of Thiosemicarbazones

Gastaca, B. , Galletti, G. , Sánchez, H. , Diez, R. , Schiavoni, M. and Furlong, J. (2015) GC/MS Analyses of Thiosemicarbazones Synthesized from Acetophenones: Thermal Decay and Mass Spectra Features. International Journal of Analytical Mass Spectrometry and Chromatography, 3, 1-13. doi: 10.4236/ijamsc.2015.31001.