Author(s)

Ekkasit Tharavichitkul^1*, Sukon Prasitwattanaseree², Patrinee Traisathit², Cholthicha Thipmate², Somvilai Chakrabandhu¹, Pitchayaponne Klunklin¹, Wimrak Onchan¹, Razvan M. Galalae³, Imjai Chitapanarux¹

¹The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
²Biostatistics and Applied Statistics Laboratory, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
³Faculty of Medicine, Christian-Albretch University, Kiel, Germany.

Purpose: To report the retrospective study of external beam radiotherapy (EBRT) ± intravaginal brachytherapy (IVBT) as adjuvant treatment for endometrial cancer. Materials and Methods: From 2001-2009, 152 patients received complete surgical staging for endometrial carcinoma and were designed by a multidisciplinary team to receive EBRT ± IVBT. The treatment results and late toxicities were evaluated and recorded. Results: At the median follow-up time of 43 months, the disease-free survival, metastasis-free survival and overall survival rates were 96.9%, 96.9% and 96.9%, respectively. Stage and age showed the statistical significance with the p-value of less than 0.001. From five to ten percent of patients developed Grades 1-2 late gastrointestinal and genitourinary toxicities, respectively. Conclusion: The using of adjuvant EBRT ± IVBT for endometrial carcinoma yielded treatment results and acceptable toxicities.

Endometrial Cancer, Adjuvant Treatment, External Beam Radiotherapy

Tharavichitkul, E. , Prasitwattanaseree, S. , Traisathit, P. , Thipmate, C. , Chakrabandhu, S. , Klunklin, P. , Onchan, W. , Galalae, R. and Chitapanarux, I. (2015) Adjuvant External Beam Radiotherapy ± Brachytherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University. Journal of Cancer Therapy, 6, 115-121. doi: 10.4236/jct.2015.62012.