Author(s)

Jingfan Yao^1,2,3,4, Zaizhu Han⁵, Yanli Song^1,2,3,4, Lei Li^1,2,3,4, Yun Zhou^1,2,3,4, Weikang Chen⁶, Yongmei Deng^1,2,3,4, Yongjun Wang^1,2,3,4, Yumei Zhang^1,2,3,4

¹Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
²China National Clinical Research Center for Neurological Diseases, Beijing, China.
³Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.
⁴Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China.
⁵State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
⁶The Sixth Affiliated Hospital of Wenzhou Medical University Lishui City People’s Hospital, Lishui, China.

Aim: To explore what is the relationship of the types of post-stroke aphasia with sex, age and stroke types. Methods: Retrospective analysis was administrated on data of 421 patients with acute stroke. Western battery aphasia was used to measure aphasiac type and aphasia quotient (AQ) score. The patients were divided into three age groups: young, middle-aged and elderly. The stroke types were classified into cerebral infraction (CI) and intracerebral hemorrhage (ICH). Results: All subjects were right-handed, which males and females accounted for 69.60% and 30.40%, respectively. There were 116 cases of Broca’s aphasia (85 males), 35 cases of Wernicke’s aphasia (20 males), 15 cases of conductive aphasia (10 males), 63 cases of transcortical motor aphasia (50 males), 11 cases of transcortical sensory aphasia (8 males), 27 cases of transcortical combined aphasia (13 males), 73 cases of anomic aphasia (47 males) and 81 cases of global aphasia (60 males). Male patients (69.60%) have a significantly higher morbidity of aphasia than that of females (30.40%) after stroke (χ² = 11.57, P = 0.003), especially those under 65 years old (73.38%). For people 65 years and older, the morbidity of female (42.97%) tends to increase with age. Sex has no significant influence on the types of aphasia (χ² = 13.84, P = 0.054). Broca’s aphasia is the most common type inboth male and female (29.01%, 24.22%, respectively). The distribution of aphasic types has no obvious difference among three age groups (χ² = 14.94, P= 0.382). Aphasia induced by CI (306 cases) is more common than that by ICH (115 cases), but there was no difference in distribution of types of aphasia (χ² = 13.23, P = 0.067). Conclusions: Male patients have a significantly higher level of morbidity of aphasia than females after stroke and a lower average age of onset than females. Broca’s aphasia is the most common one in both male and female. Broca’s aphasia, global and anomic aphasia are the most common aphasic types in both CI and ICH patients, except the female with ICH.

Type of Aphasia, Sex, Age, Type of Stroke

Yao, J. , Han, Z. , Song, Y. , Li, L. , Zhou, Y. , Chen, W. , Deng, Y. , Wang, Y. and Zhang, Y. (2015) Relationship of Post-Stroke Aphasic Types with Sex, Age and Stroke Types. World Journal of Neuroscience, 5, 34-39. doi: 10.4236/wjns.2015.51004.