Author(s)

Nobuo Yamaguchi^1,2*, Keiko Matsuba², Kazuhiro Okamoto³, Takanao Ueyama⁴, Yoshiichiroh Matsuba², Katsuko Okuzumi⁵, Ikkan Watanabe², Takashi Takahashi⁵

¹Department of Fundamental Research for CAM, Kanazawa Medical University, Uchinada, Japan.
²Ishikawa Natural Medicinal Products Research Center, Kanazawa, Japan.
³Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
⁴Department of Medicine II, Kansai Medical University, Osaka, Japan.
⁵Laboratories of Infectious Diseases, Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.

Phagocytic cells are known as multi potent activities for its ontogenical and phylogenetical aspect. One of the strike actions is super oxide anion known as critical role of the cell when microorganisms invade inside the cytoplasm. This agent sometimes triggered as a serious factor in the site of inflammation. There are many papers which concerned newly accessed anti-oxidative substances. However, many reports only focused on the molecular basis in vitro, suggesting vin rouge for their rich content of polyphonol rather than vin blank with a French paradox. We had been suggested that the key factor for oxidative stress needs to be discussed first for immunological standpoint, such as in phagocytic cell in situ. With this assay system in rodent macrophage, SO level was about the same for both groups administered vin blank as well as vin rouge.

Super Oxide Anion, Anti-Oxidant Sample, Neutrophyl, Macrophage, Vin Blank, Vin Rouge, In Situ Estimation

Yamaguchi, N. , Matsuba, K. , Okamoto, K. , Ueyama, T. , Matsuba, Y. , Okuzumi, K. , Watanabe, I. and Takahashi, T. (2014) Rodent Macrophage Select Vin Blank Together with Vin Rouge According to SO Level in Situ. Open Journal of Rheumatology and Autoimmune Diseases, 4, 240-247. doi: 10.4236/ojra.2014.44033.