Share This Article:

Synthesis and Guest-Binding Behavior of Water-Soluble Cyclophanes Bearing PEG Residues

Full-Text HTML XML Download Download as PDF (Size:2880KB) PP. 409-416
DOI: 10.4236/aces.2014.44045    2,988 Downloads   3,502 Views Citations

ABSTRACT

A water-soluble cyclophane (1) having poly(ethylene glycol) (PEG) moieties has been prepared from a tetraazide-functionalized cyclophane derivative and four poly(ethylene glycol) methyl ether acetylenes by Cu(I)-catalyzed 1,3 dipolar cycloadditions (click chemistry). An analogous derivative having a pyrene moiety (2) was also prepared in a similar manner. The guest-binding behavior of 1 and 2 toward anionic guests such as 6-p-toluidinonaphthalene-2-sulfonate was investigated by fluorescence spectroscopy. The binding constants (K) of the host-guest complexes were evaluated.

Cite this paper

Hayashida, O. , Nakamura, Y. and Sato, T. (2014) Synthesis and Guest-Binding Behavior of Water-Soluble Cyclophanes Bearing PEG Residues. Advances in Chemical Engineering and Science, 4, 409-416. doi: 10.4236/aces.2014.44045.

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.