The study was designed to prioritize a plethora of factors that may affect or impede the success of implementing a MICE professional English program as an educational innovation at a tertiary context in Taiwan. Through the utilization of modified Delphi method and analytic hierarchy analysis (AHP), priorities were generated in a comprehensive format pertaining to the top five factors critical to successful implementation of the intended program. The study offers practical implementations by pointing to the importance of detecting highly prioritized factors. It was recommended that the intended group of implementers reduce the hindering factors and maximize the supportive ones for all engaged in the implementation process. The method introduced will help future researchers understand how ESP programs can be implemented effectively in other settings to achieve maximum impact. Several practical and research implications were discussed.