A Modified Method for the Synthesis of Tetradentate Ligand Involving Peptide Bond

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DOI: 10.4236/ijoc.2014.42014    4,586 Downloads   7,031 Views  Citations

ABSTRACT

In view of the importance of picolinic acid (Pa) in preventing cell growth and arresting cell cycle, attempts were made to design, synthesize and characterize two new Pa based tetradentate ligands (DPPTR and DPPTY) with a modified procedure. The procedure reported here avoids by-products and provides better yield and purity.

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Reddy, P. , Chandrashekar, R. , Shaik, H. and Satyanarayana, B. (2014) A Modified Method for the Synthesis of Tetradentate Ligand Involving Peptide Bond. International Journal of Organic Chemistry, 4, 122-134. doi: 10.4236/ijoc.2014.42014.

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