Author(s)

Aly H. Atta, Ahmed I. El-Shenawy, Fathy A. Koura, Moamen S. Refat

Department of Chemistry, Faculty of Education, University of Dammam, Dammam, KSA; Department of Chemistry, Faculty of Science, Benha University, Benha, Egypt.
Department of Chemistry, Faculty of Education, University of Dammam, Dammam, KSA; Department of Chemistry, Faculty of Science, Suez University, Suez, Egypt.
Department of Chemistry, Faculty of Education, University of Dammam, Dammam, KSA;Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, Egypt.
Department of Chemistry, Faculty of Science, Taif University, Al-Hawiah, KSA;Department of Chemistry, Faculty of Science, Port Said University, Port Said, Egypt.

Selenium (IV) vitamin A complex as antioxidant drug design was prepared and characterized by microanalysis, conductance, infrared spectra, Raman laser spectra, 1HNMR spectra, scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and thermogravimetric (TG/DTG and DTA) tool of analyses. Vitamin A chelate was coordinated as a mono-dentate ligand through the oxygen atom of –OH hydroxyl group. Thermal degradation analyses discussed the removal of terminal methyl molecules in the first and second decomposition stage while the organic ligand moieties existed in the third and subsequence steps. The Se (IV) complex in comparable with free vitamin A ligand has been assessed against some kinds of bacteria and fungi which gave a significant inhibition. The surface morphology and nano scale size of selenium metal and its vitamin complex were proved. The activation energy and other thermodynamic parameters (ΔH*, ΔS* and ΔG*) of Se (IV) complex were calculated using Coats-Redfern and Horowitz-Metzger equations.

Vitamin A, Selenium, Nano-Scale, Spectroscopic, Thermal Analysis, Antimicrobial Activity

Atta, A. , El-Shenawy, A. , Koura, F. and Refat, M. (2014) Synthesis and Characterization of Some Selenium Nanometric Compounds: Spectroscopic, Biological and Antioxidant Assessments. World Journal of Nano Science and Engineering, 4, 58-69. doi: 10.4236/wjnse.2014.42009.