For Real Estate industry which has many types of enterprises, how to carry on the effective clustering analysis has become a problem that needs to solve. This paper first theoretically elaborates the SOM network, and then pretreats the data with SOM network, which has the ability to deal with the high dimensional and complex data. Finally it uses the clustering function of SOM neural network to make clustering analysis and comparison of Real Estate companies which are listed in Shanghai and Shenzhen stock market. The clustering analysis results based on SOM are displayed in two-dimensional graphics, showing intuitively and comprehensively of the financial situation of each enterprise.