Author(s)

Shadi Abu-Baker, Philip Garber, Bryce Hina, Trevor Reed, Ghaffari Shahrokh, Mohannad Al-Saghir, Gary Lorigan

College of Arts and Sciences, Ohio University, Zanesville, USA.
College of Arts and Sciences, Ohio University, Zanesville, USA; Genesis Hospital, Ohio University, Zanesville, USA.
Department of Chemistry and Biochemistry, Miami University, Oxford, USA.

In this study, we report the microwave assisted synthesis of Phospholamban protein (WT-PLB) as a new gold standard in solid phase peptide synthesis. Microwave energy offers benefits for both the coupling and deprotection reactions during peptide synthesis. The use of microwave energy for both the coupling and deprotection steps makes the microwave peptide synthesizers the most versatile and powerful systems available. It produces high yield and fast synthesis when compared to conventional peptide synthesizers.

Solid-State Peptide Synthesis; Phospholamban; Microwave Assisted Synthesis

S. Abu-Baker, P. Garber, B. Hina, T. Reed, G. Shahrokh, M. Al-Saghir and G. Lorigan, "Microwave Assisted Peptide Synthesis as a New Gold Standard in Solid Phase Peptide Synthesis: Phospholamban as an Example," Open Journal of Synthesis Theory and Applications, Vol. 3 No. 1, 2014, pp. 1-4. doi: 10.4236/ojsta.2014.31001.