Author(s)

Hishame Abd-Elnabi, Afaf Mohamed Abdel Hameed, Ramadan Ahmed Mekheimer, Reham R. Awed, Kamal Usef Sadek

Department of Chemistry, Faculty of Science, El-Minia University, El-Minia, Egypt.
Department of Chemistry, Faculty of Science, El-Minia University, El-Minia, Egypt; Department of Chemistry, Faculty of Science for Girls, King Abdulaziz University, Jeddah, KSA.

A simple, green and highly efficient procedure for the Biginelli condensation reaction of aldehydes, β-ketoesters, urea or thiourea catalyzed by crushed garlic clove at ambient temperature is reported.

Garlic Glove; Biocatalysis; Water; Biginelli Reaction

H. Abd-Elnabi, A. Mohamed Abdel Hameed, R. Ahmed Mekheimer, R. R. Awed and K. Usef Sadek, "Garlic Clove Catalyzed Biginelli Reaction in Water at Ambient Temperature," Green and Sustainable Chemistry, Vol. 3 No. 4, 2013, pp. 141-145. doi: 10.4236/gsc.2013.34017.