Electronic Detection of Escherichia coli O157︰H7 Using Single-Walled Carbon Nanotubes Field-Effect Transistor Biosensor - Engineering

ENG > Vol.4 No.10, October 2012

Electronic Detection of Escherichia coli O157︰H7 Using Single-Walled Carbon Nanotubes Field-Effect Transistor Biosensor ()

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DOI: 10.4236/eng.2012.410B024 3,654 Downloads 5,759 Views Citations

Author(s)

Xiaoxian Zhang, Dongwei Wang, Danna Yang, Sai Li, Zhiqiang Shen

Affiliation(s)

Academy of Military Medical sciences, Chinese PLA Center for Disease Control & Prevention, Tianjin, China.
School of Chemical Engineering, Sichuan University, Chengdu, China.

ABSTRACT

Field effect transistors (FET) based on Single-Walled Carbon Nanotubes (SWNTs) become the hot topic in fields of nano-electronic, clinical diagnostics, environmental testing etc. in recent years. In this paper, we reported a simple, scalable way to enrich semiconducting SWNTs by using HNO₃/H₂SO₄. Then carbon nanotube field-effect transistors (CNTFET) biosensor was fabricated with the enrichment SWNTs for Escherichia coli O157︰H7 detection. The response of each CNTFET was monitored in real time before and after introduction of the Escherichia coli O157︰H7 at various concentrations. The results show that CNT-FET biosensors we fabricated are sensitive to change of concentration of solution and response time is really short.

KEYWORDS

Single-walled Carbon Nanotubes (SWNTs); Field Effect Transistors; Biosensor; Escherichia Coli O157︰H7

Share and Cite:

X. Zhang, D. Wang, D. Yang, S. Li and Z. Shen, "Electronic Detection of Escherichia coli O157︰H7 Using Single-Walled Carbon Nanotubes Field-Effect Transistor Biosensor," Engineering, Vol. 4 No. 10B, 2012, pp. 94-98. doi: 10.4236/eng.2012.410B024.

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