This study proposes to identify the determinants of accepting e-learning by the employees of the Tunisian Post Office using the Technology Acceptance Model (TAM). An empirical study was conducted over a sample of 200 Tunisian employees. Our results indicated that for the Tunisian employees perceived usefulness, perceived ease of use, mastery of new information and communication technologies (NICT) as individual factors as well as the proposed technique as an organisational factor represented the main determinants of e-learning acceptance.