Prolonged coexistent central diabetes insipidus and cerebral salt wasting syndrome following neurosurgery

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DOI: 10.4236/ojped.2013.32014    5,298 Downloads   8,517 Views  Citations

ABSTRACT

The coexistence of different water homeostasis abnormalities following neurosurgery represents a diagnostic and therapeutic challenge for intensive care units. This paper reports the case of a 13 year-old boy who underwent surgery for a suprasellar tumour and, immediately after surgery, developed a cerebral abscess, persistent diabetes insipidus (DI) as well as cerebral salt wasting syndrome (CSWS). The early onset of CSWS following DI has been associated with a poor prognosis and increased mortality. In cases in which these abnormalities coexist, the increased polyuria secondary to the rise in natriuresis associated with CSWS might be erroneously interpreted as a sign of poor control of the DI, thereby leading to therapeutic mistakes. Treatment basically consists of restoring electrolytes and the joint administration of desmopressin and fludrocortisone.

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Lara, D. , Joyanes, B. , Llaneza, A. , Pérez, O. , Llorente, B. and Runkle, I. (2013) Prolonged coexistent central diabetes insipidus and cerebral salt wasting syndrome following neurosurgery. Open Journal of Pediatrics, 3, 74-77. doi: 10.4236/ojped.2013.32014.

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