The paper concludes that the energy given by Einstein’s famous formula E = mc² consists of two parts. The first part is the positive energy of the quantum particle modeled by the topology of the zero set. The second part is the absolute value of the negative energy of the quantum Schr?dinger wave modeled by the topology of the empty set. We reason that the latter is nothing else but the so called missing dark energy of the universe which accounts for 94.45% of the total energy, in full agreement with the WMAP and Supernova cosmic measurement which was awarded the 2011 Nobel Prize in Physics. The dark energy of the quantum wave cannot be detected in the normal way because measurement collapses the quantum wave.