Churg-Strauss Syndrome Revealed by Acute Coronary Artery Disease: A Case Report* - Open Journal of Respiratory Diseases

OJRD > Vol.3 No.2, May 2013

Churg-Strauss Syndrome Revealed by Acute Coronary Artery Disease: A Case Report* ()

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DOI: 10.4236/ojrd.2013.32007 3,922 Downloads 6,403 Views Citations

Author(s)

Maurice Estivals, Marc Périé, Daniel Colombier, Bruno Farah

Affiliation(s)

Department of Cardiology, CHT G. Bourret, Nouméa, New Caledonia.
Department of Interventional Cardiology, Clinique Pasteur, Toulouse, France.
Department of Pulmonology, H?pital du Pays d’Autan, Castres, France.
Department of Radiology, Clinique Pasteur, Toulouse, France.

ABSTRACT

Churg-Strauss syndrome (CSS) is a very rare small-vessel vasculitis. Clinical features include asthma, rhinitis and/or sinusitis, and peripheral eosinophilia. Although cardiac findings are observed in 50% of cases, coronary artery disease is rarely reported and even more rarely suggestive. The value of cardiac MRI for these patients is discussed here. A 52-year-old non-smoker male without family antecedents of cardiovascular disease presented with worsening of atypical asthma that developed 10 months earlier. A month before, he had been admitted to the ICU because of respiratory distress and cardiogenic shock with chest pain. The angiogram revealed stenosis of the three main coronary arteries requiring the placement of several stents. Follow-up cardiac assessments showed good results. General impairment, unstable asthma associated with rhinitis, and eosinophilia suggested a systemic disease. The diagnosis of CSS was established considering that five criteria of the American College of Rheumatology were found. Prednisolone was prescribed at 1 mg/kg/day, which completely suppressed all symptoms and eosinophilia. Cardiac MRI was performed two months later and revealed a good control of myocardial lesions characterized by fibrosis beneath the anterior endocardium and the median septum. Immunosuppressive treatment was then administered together with corticosteroid therapy. These results suggest that acute coronary artery disease can reveal CSS in some cases. Here, the patient’s cardiac assessment was normal apart from the acute episode, and cardiac MRI helped detect signs of myocarditis and establish a prognosis of CSS.

KEYWORDS

Vasculitis; Churg-Strauss Syndrome; Acute Coronary Artery Disease; Eosinophilia; Cardiac MRI

Share and Cite:

Estivals, M. , Périé, M. , Colombier, D. and Farah, B. (2013) Churg-Strauss Syndrome Revealed by Acute Coronary Artery Disease: A Case Report*. Open Journal of Respiratory Diseases, 3, 39-43. doi: 10.4236/ojrd.2013.32007.

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