We present the case of a 51-year-old moderate hemophiliac with gingival bleeding due to papillary inflammation and adherence in the molar area 47. After dental diagnosis a calculus was removed and 30% trichloroacetic acid was placed by a pressurized applicator for five seconds; the procedure was repeated until the bleeding stopped, then tranexamic acid was placed by a gauze. The patient chewed the gauze for 30 minutes and was discharged after repeating the same procedure for 30 minutes more. We observed how local treatment with trichloroacetic acid combined to tranexamic acid placed on the hemorrhagic site was able to stop the bleeding.