Author(s)

Heiko Baumann, Eduard Schlegel, Fabian Wagner, Jürgen Biscoping

St. Vincentius-Kliniken gAG, Department of Anesthesia and Intensive Care, Steinh?userstr. Karlsruhe, Germany.

The anesthetic implications of caring for patients with mitochondrial myopathies (MM) are not well defined, and the few case reports that have been published are contradictory. Local anesthetics particularly have the potential to worsen neuromuscular manifestations via direct effects on mitochondrial bioenergetics. Here we describe the anesthetic management of a patient with chronic progressive external ophthalmoplegia (CPEO) in which a sciatic nerve block with ropivacaine and prilocaine was performed and review the available related literature.

Local Anesthetics; Mitochondrial Myopathy; Sciatic Nerve Block; Pharmacology; Anesthetic Management

H. Baumann, E. Schlegel, F. Wagner and J. Biscoping, "Sciatic Nerve Block with Ropivacaine and Prilocaine in a Patient with Chronic Progressive External Ophthalmoplegia (CPEO)," Open Journal of Anesthesiology, Vol. 2 No. 4, 2012, pp. 117-119. doi: 10.4236/ojanes.2012.24027.