Author(s)

Moritz Metlitzky, Sandra Puehringer, Stuart J. Fisher

Department of Molecular Biology, University of Salzburg, Salzburg, Austria.

Pyrroloquinoline quinone (PQQ) is an important redox-active cofactor for many bacterial dehy-drogenases. It's biosynthetic pathway involves six or seven genes, one of which is pqqB. Former studies indicated that the protein encoded by pqqB, namely PqqB, functions as a PQQ transporter. Here we report the crystal structure of PqqB from Pseudomonas putida at 2.2 ? resolution together with functional studies to verify this theory.

PqqB; PQQ; Biosynthetic Pathway; X-Ray Crystallography

Metlitzky, M. , Puehringer, S. and J. Fisher, S. (2012) Crystal structure of PqqB from Pseudomonas putida at 2.2 Å resolution. Journal of Biophysical Chemistry, 3, 206-210. doi: 10.4236/jbpc.2012.32023.